Welcome to the cruise port guide San Diego. San Diego is a port of call often included in Panama Canal and Pacific cruises. It receives almost 100 cruise ship calls every year. It is California’s 2nd largest city and perhaps best known for its beaches, incredible weather and fun tourist attractions. Arriving in San Diego by cruise ship is a privilege. Your ship will pass the tip of Point Loma, enter the San Diego Bay and approach beautiful downtown San Diego. Be sure to keep those cameras ready. Read where your ship will dock in the San Diego cruise port guide underneath. san-diego-cruise-destination